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TargetUTS2R
LigandBDBM50413775
Substrate/Competitorn/a
Meas. Tech.ChEMBL_523641
EC50 6.03±n/a nM
Citation Grieco PCarotenuto ACampiglia PGomez-Monterrey IAuriemma LSala MMarcozzi Cd'Emmanuele di Villa Bianca RBrancaccio DRovero PSanticioli PMeini SMaggi CANovellino E New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide. J Med Chem 52:3927-40 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
UTS2R
Name:UTS2R
Synonyms:G-protein coupled receptor 14 | G-protein coupled sensory epithelial neuropeptide-like receptor | SENR | UR-II-R | Urotensin-II
Type:Enzyme Catalytic Domain
Mol. Mass.:42725.34
Organism:RAT
Description:Urotensin-II UTS2R RAT::P49684
Residue:386
Sequence:
MALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSA
MGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGD
VGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLL
TLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWL
SQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNY
LTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSG
RSLSSSSQQATETLMLSPVPRNGALL
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  Blast E-value cutoff:
BDBM50413775
n/a
NameBDBM50413775
Synonyms:CHEMBL501794
TypeSmall organic molecule
Emp. Form.C54H75N11O10S2
Mol. Mass.1102.371
SMILESCC(C)[C@H](NC(=O)[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r|
Structure
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