| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2A5 |
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| Ligand | BDBM82070 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_572014 (CHEMBL1023676) |
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| IC50 | 159956±n/a nM |
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| Citation |  Roy, K; Roy, PP Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques. Eur J Med Chem44:1941-51 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2A5 |
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| Name: | Cytochrome P450 2A5 |
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| Synonyms: | CP2A5_MOUSE | Cyp2a-5 | Cyp2a5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56752.73 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_572014 |
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| Residue: | 494 |
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| Sequence: | MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNFLQLNTEQMYNSLMK
ISQRYGPVFTIYLGPRRIVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVVFSS
GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSN
VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPGPQQQAFKE
LQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFF
AGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQ
RFADMIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDK
GQFKKNDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVGF
ATIPPTYTMSFLSR
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| BDBM82070 |
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| n/a |
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| Name | BDBM82070 |
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| Synonyms: | CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D salicylate | US10667515, Compound (S)-nicotine | US9303017, Nicotine |
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| Type | n/a |
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| Emp. Form. | C10H14N2 |
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| Mol. Mass. | 162.2316 |
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| SMILES | CN1CCC[C@H]1c1cccnc1 |r| |
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| Structure | 
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