| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50284000 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_570538 (CHEMBL1026910) |
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| Ki | 9.51±n/a nM |
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| Citation |  De Freitas, GB; da Silva, LL; Romeiro, NC; Fraga, CA Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors. Eur J Med Chem44:2482-96 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50284000 |
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| n/a |
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| Name | BDBM50284000 |
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| Synonyms: | (2-Methyl-1-pentyl-1H-indol-3-yl)-naphthalen-1-yl-methanone | (2-Methyl-1-pentyl-1H-indol-3-yl)-naphthalen-1-yl-methanone (JWH-018) | (2-methyl-1-pentyl-1H-indol-3-yl)(naphthalen-1-yl)methanone | CHEMBL306529 | JWH-007 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25NO |
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| Mol. Mass. | 355.4721 |
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| SMILES | CCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc12 |
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| Structure | 
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