| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50415111 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_597715 (CHEMBL1043502) |
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| EC50 | 79.43±n/a nM |
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| Citation |  Gleave, RJ; Beswick, PJ; Brown, AJ; Giblin, GM; Haslam, CP; Livermore, D; Moses, A; Nicholson, NH; Page, LW; Slingsby, B; Swarbrick, ME 2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships. Bioorg Med Chem Lett19:6578-81 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50415111 |
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| n/a |
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| Name | BDBM50415111 |
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| Synonyms: | CHEMBL570683 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25Cl2N3O2 |
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| Mol. Mass. | 434.359 |
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| SMILES | Clc1cccc(-c2cnc(N3CCCCCC3)c(c2)C(=O)N2CCOCC2)c1Cl |
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| Structure | 
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