| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50415189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_601035 (CHEMBL1069172) |
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| Ki | 46.77±n/a nM |
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| Citation |  Balo, MC; Brea, J; Caamaño, O; Fernández, F; García-Mera, X; López, C; Loza, MI; Nieto, MI; Rodríguez-Borges, JE Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists. Bioorg Med Chem17:6755-60 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50415189 |
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| n/a |
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| Name | BDBM50415189 |
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| Synonyms: | CHEMBL595657 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20F2N4O3 |
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| Mol. Mass. | 426.416 |
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| SMILES | Cn1c(Cc2c(F)cccc2F)nc2n(Cc3ccco3)c(=O)n(CC3CC3)c(=O)c12 |
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| Structure | 
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