| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 9 |
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| Ligand | BDBM50415620 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_621737 (CHEMBL1108469) |
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| IC50 | 1258.93±n/a nM |
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| Citation |  Christopher, JA; Atkinson, FL; Bax, BD; Brown, MJ; Champigny, AC; Chuang, TT; Jones, EJ; Mosley, JE; Musgrave, JR 1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3. Bioorg Med Chem Lett19:2230-4 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 9 |
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| Name: | Mitogen-activated protein kinase 9 |
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| Synonyms: | JNK-55 | JNK2 | JNK2/JNK3 | MAPK9 | MK09_HUMAN | Mitogen-Activated Protein Kinase 9 (JNK2) | Mitogen-activated protein kinase 8/9 | PRKM9 | SAPK1A | Stress-activated protein kinase JNK2 | c-Jun N-terminal kinase 2 | c-Jun N-terminal kinase 2 (JNK2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 48131.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | JNK-2 was purchased from Upstate Cell Signaling Solutions (formerly Upstate Biotechnology). |
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| Residue: | 424 |
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| Sequence: | MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
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| BDBM50415620 |
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| n/a |
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| Name | BDBM50415620 |
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| Synonyms: | CHEMBL1088633 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13Cl2NO |
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| Mol. Mass. | 306.187 |
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| SMILES | COc1cc2CCN=C(c3cccc(Cl)c3)c2cc1Cl |t:7| |
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| Structure | 
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