Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Acetylcholine-binding protein | ||
| Ligand | BDBM50417091 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_665337 (CHEMBL1261014) | ||
| Kd | 871±n/a nM | ||
| Citation |  de Kloe, GE; Retra, K; Geitmann, M; Källblad, P; Nahar, T; van Elk, R; Smit, AB; van Muijlwijk-Koezen, JE; Leurs, R; Irth, H; Danielson, UH; de Esch, IJ Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptora7 ligands. J Med Chem53:7192-201 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Acetylcholine-binding protein | |||
| Name: | Acetylcholine-binding protein | ||
| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP | ||
| Type: | n/a | ||
| Mol. Mass.: | 26055.52 | ||
| Organism: | Lymnaea stagnalis | ||
| Description: | Soluble acetylcholine receptor | ||
| Residue: | 229 | ||
| Sequence: |
| ||
| BDBM50417091 | |||
| n/a | |||
| Name | BDBM50417091 | ||
| Synonyms: | CHEMBL1258127 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H24N4O | ||
| Mol. Mass. | 336.4308 | ||
| SMILES | O=C(N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1)Nc1ccccc1 |r,wU:3.2,wD:10.12,TLB:11:10:6.5:8.9,THB:2:3:6.5:8.9,(6.76,4.22,;6.78,5.76,;5.45,6.55,;4.11,5.8,;2.64,6.44,;1.29,5.83,;1.01,4.44,;2.38,5.07,;2.13,6.97,;2.57,8.09,;3.92,4.42,;4.68,3.08,;3.89,1.75,;2.35,1.77,;1.57,.44,;2.33,-.9,;3.88,-.91,;4.66,.42,;8.12,6.52,;9.45,5.73,;9.42,4.19,;10.75,3.4,;12.09,4.15,;12.11,5.7,;10.78,6.48,)| | ||
| Structure | 
| ||