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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Acetylcholine-binding protein | ||
| Ligand | BDBM50393248 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_665337 (CHEMBL1261014) | ||
| Kd | 93±n/a nM | ||
| Citation |  de Kloe, GE; Retra, K; Geitmann, M; Källblad, P; Nahar, T; van Elk, R; Smit, AB; van Muijlwijk-Koezen, JE; Leurs, R; Irth, H; Danielson, UH; de Esch, IJ Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptora7 ligands. J Med Chem53:7192-201 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Acetylcholine-binding protein | |||
| Name: | Acetylcholine-binding protein | ||
| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP | ||
| Type: | n/a | ||
| Mol. Mass.: | 26055.52 | ||
| Organism: | Lymnaea stagnalis | ||
| Description: | Soluble acetylcholine receptor | ||
| Residue: | 229 | ||
| Sequence: |
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| BDBM50393248 | |||
| n/a | |||
| Name | BDBM50393248 | ||
| Synonyms: | CHEMBL1258005 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22BrN3O | ||
| Mol. Mass. | 400.312 | ||
| SMILES | Brc1ccc(cc1)C(=O)N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1 |r,wU:10.10,wD:17.20,TLB:18:17:13.12:15.16,THB:9:10:13.12:15.16,(-.69,-12.68,;-2.04,-13.43,;-2.06,-14.97,;-3.4,-15.72,;-4.72,-14.94,;-4.71,-13.4,;-3.37,-12.64,;-6.06,-15.69,;-6.08,-17.23,;-7.38,-14.9,;-8.73,-15.65,;-10.2,-15.01,;-11.56,-15.62,;-11.84,-17.01,;-10.46,-16.38,;-10.71,-14.48,;-10.27,-13.37,;-8.92,-17.03,;-8.16,-18.37,;-8.94,-19.7,;-10.48,-19.68,;-11.28,-21.01,;-10.51,-22.35,;-8.96,-22.36,;-8.18,-21.03,)| | ||
| Structure | 
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