Reaction Details | |||
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Target | Acetylcholine-binding protein | ||
Ligand | BDBM50417095 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_665337 (CHEMBL1261014) | ||
Kd | 18621±n/a nM | ||
Citation | de Kloe, GE; Retra, K; Geitmann, M; Källblad, P; Nahar, T; van Elk, R; Smit, AB; van Muijlwijk-Koezen, JE; Leurs, R; Irth, H; Danielson, UH; de Esch, IJ Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptora7 ligands. J Med Chem53:7192-201 (2010) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Acetylcholine-binding protein | |||
Name: | Acetylcholine-binding protein | ||
Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP | ||
Type: | n/a | ||
Mol. Mass.: | 26055.52 | ||
Organism: | Lymnaea stagnalis | ||
Description: | Soluble acetylcholine receptor | ||
Residue: | 229 | ||
Sequence: |
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BDBM50417095 | |||
n/a | |||
Name | BDBM50417095 | ||
Synonyms: | CHEMBL1255909 | ||
Type | Small organic molecule | ||
Emp. Form. | C14H19N3O | ||
Mol. Mass. | 245.3202 | ||
SMILES | O=C(N[C@H]1CN2CCC1CC2)Nc1ccccc1 |r,wU:3.2,THB:2:3:6.7:10.9,(7.58,-28.23,;7.6,-26.69,;6.27,-25.9,;4.93,-26.65,;4.74,-28.04,;3.2,-27.38,;1.83,-28.02,;2.11,-26.62,;3.46,-26.01,;3.39,-24.37,;2.94,-25.48,;8.94,-25.94,;10.27,-26.73,;10.24,-28.27,;11.57,-29.06,;12.92,-28.3,;12.93,-26.75,;11.61,-25.97,)| | ||
Structure |