| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50417764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_701282 (CHEMBL1648902) |
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| IC50 | 0.398±n/a nM |
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| Citation |  Mu, L; Aguiar, J; Ardati, A; Cao, B; Gardner, CJ; Gillespy, T; Harris, K; Lim, S; Marcus, R; Morize, I; Parkar, A; Stefany, D; Li, Y; Vaz, RJ; Cirovic, DA Understanding DP receptor antagonism using a CoMSIA approach. Bioorg Med Chem Lett21:66-75 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50417764 |
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| n/a |
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| Name | BDBM50417764 |
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| Synonyms: | CHEMBL1644227 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N7O2 |
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| Mol. Mass. | 403.4371 |
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| SMILES | COc1ccc(CCNc2cc(nc(OC)n2)-c2cccc(c2)-c2nnn[nH]2)cc1 |
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| Structure | 
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