| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 2B6 |
|---|
| Ligand | BDBM50418087 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_738478 (CHEMBL1743379) |
|---|
| Ki | 5100±n/a nM |
|---|
| Citation |  Fontana, E; Dansette, PM; Poli, SM Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab6:413-54 (2005) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 2B6 |
|---|
| Name: | Cytochrome P450 2B6 |
|---|
| Synonyms: | CP2B6_HUMAN | CYP2B6 | Cytochrome P450 2B6 (CYP2B6) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 56289.75 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P20813 |
|---|
| Residue: | 491 |
|---|
| Sequence: | MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFRE
KYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNR
WKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC
SIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQE
INAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGT
ETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFS
DLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGAL
KKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKI
PPTYQIRFLPR
|
|
|
|---|
| BDBM50418087 |
|---|
| n/a |
|---|
| Name | BDBM50418087 |
|---|
| Synonyms: | CHEMBL1743351 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12Cl2N2O3 |
|---|
| Mol. Mass. | 351.184 |
|---|
| SMILES | COc1ccc(cc1OCC#C)C(=O)Nc1c(Cl)cncc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
