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TargetfMet-Leu-Phe receptor
LigandBDBM50418361
Substrate/Competitorn/a
Meas. Tech.ChEMBL_744724 (CHEMBL1772745)
IC50 1259±n/a nM
Citation Unitt, JFagura, MPhillips, TKing, SPerry, MMorley, AMacDonald, CWeaver, RChristie, JBarber, SMohammed, RPaul, MCook, ABaxter, A Discovery of small molecule human FPR1 receptor antagonists. Bioorg Med Chem Lett21:2991-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
fMet-Leu-Phe receptor
Name:fMet-Leu-Phe receptor
Synonyms:FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:Enzyme Catalytic Domain
Mol. Mass.:38456.14
Organism:Homo sapiens (Human)
Description:gi_4503779
Residue:350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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  Blast E-value cutoff:
BDBM50418361
n/a
NameBDBM50418361
Synonyms:CHEMBL1770153
TypeSmall organic molecule
Emp. Form.C23H22N2O3
Mol. Mass.374.4324
SMILESCc1cccc(C)c1NC(=O)C(NC(=O)c1ccccc1O)c1ccccc1
Structure
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