| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM50418334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_744770 (CHEMBL1772791) |
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| IC50 | 25119±n/a nM |
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| Citation |  Unitt, J; Fagura, M; Phillips, T; King, S; Perry, M; Morley, A; MacDonald, C; Weaver, R; Christie, J; Barber, S; Mohammed, R; Paul, M; Cook, A; Baxter, A Discovery of small molecule human FPR1 receptor antagonists. Bioorg Med Chem Lett21:2991-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1_MOUSE | Fpr1 | N-formyl peptide receptor | N-formylpeptide chemoattractant receptor | fMLP receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40342.61 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_744770 |
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| Residue: | 364 |
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| Sequence: | MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYIVLDVFSYLIFAVTFVLGVLGNGLVIWVAG
FRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGS
VFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRL
GPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIH
RQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVRERLKNMTPGIVTALKITSPL
AFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALTEDSAQTSDTGTNLGTNSTSLSENT
LNAM
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| BDBM50418334 |
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| n/a |
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| Name | BDBM50418334 |
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| Synonyms: | CHEMBL1770298 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N2O3S |
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| Mol. Mass. | 394.487 |
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| SMILES | Cc1ccc(s1)C(NC(=O)c1ccccc1O)C(=O)Nc1c(C)cccc1C |
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| Structure | 
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