| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50418594 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_750583 (CHEMBL1786447) |
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| Ki | <1000±n/a nM |
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| Citation |  Trapella, C; Fischetti, C; Pela', M; Lazzari, I; Guerrini, R; Calo', G; Rizzi, A; Camarda, V; Lambert, DG; McDonald, J; Regoli, D; Salvadori, S Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide. Bioorg Med Chem17:5080-95 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50418594 |
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| n/a |
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| Name | BDBM50418594 |
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| Synonyms: | CHEMBL1783826 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33Cl2N3O |
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| Mol. Mass. | 474.466 |
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| SMILES | Clc1cccc(Cl)c1C1CCN(CCCNC(=O)[C@H]2CCCN2Cc2ccccc2)CC1 |r| |
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| Structure | 
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