| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50418842 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_757209 (CHEMBL1803433) |
|---|
| Ki | 12.59±n/a nM |
|---|
| Citation |  Zhukov, A; Andrews, SP; Errey, JC; Robertson, N; Tehan, B; Mason, JS; Marshall, FH; Weir, M; Congreve, M Biophysical mapping of the adenosine A2A receptor. J Med Chem54:4312-23 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50418842 |
|---|
| n/a |
|---|
| Name | BDBM50418842 |
|---|
| Synonyms: | CHEMBL1800357 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14FN5O |
|---|
| Mol. Mass. | 323.3244 |
|---|
| SMILES | Nc1nc(nc(n1)-c1ccccc1O)N1Cc2ccc(F)cc2C1 |
|---|
| Structure | 
|
|---|
Search and Browse
