| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
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| Ligand | BDBM50418933 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_758406 (CHEMBL1811272) |
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| Ki | 123026877.08±n/a nM |
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| Citation |  Thorn, K; Nielsen, CU; Jakobsen, P; Steffansen, B; Zercher, CK; Begtrup, M The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1. Bioorg Med Chem Lett21:4597-601 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 1 |
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| Name: | Solute carrier family 15 member 1 |
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| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78818.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1488839 |
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| Residue: | 708 |
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| Sequence: | MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
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| BDBM50418933 |
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| n/a |
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| Name | BDBM50418933 |
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| Synonyms: | CHEMBL1807356 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N3O6 |
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| Mol. Mass. | 456.511 |
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| SMILES | CCC[C@H](NC(=O)[C@H](COC(=O)c1ccccc1)NC(=O)[C@@H]([NH3+])Cc1ccccc1)C(O)=O |r| |
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| Structure | 
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