Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM50419048 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_766545 (CHEMBL1827026) | ||
Ki | 1.58±n/a nM | ||
Citation | Verheij, MH; de Graaf, C; de Kloe, GE; Nijmeijer, S; Vischer, HF; Smits, RA; Zuiderveld, OP; Hulscher, S; Silvestri, L; Thompson, AJ; van Muijlwijk-Koezen, JE; Lummis, SC; Leurs, R; de Esch, IJ Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A. Bioorg Med Chem Lett21:5460-4 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
Type: | Protein | ||
Mol. Mass.: | 55283.27 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P46098 | ||
Residue: | 478 | ||
Sequence: |
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BDBM50419048 | |||
n/a | |||
Name | BDBM50419048 | ||
Synonyms: | CHEMBL1824048 | ||
Type | Small organic molecule | ||
Emp. Form. | C14H16ClN3 | ||
Mol. Mass. | 261.75 | ||
SMILES | CN1CCC(CC1)=Cc1nc2ccc(Cl)cc2[nH]1 |(32.19,-17.45,;31.42,-18.78,;32.19,-20.12,;31.43,-21.45,;29.89,-21.45,;29.11,-20.13,;29.88,-18.79,;29.13,-22.78,;27.59,-22.79,;26.69,-24.05,;25.22,-23.58,;23.88,-24.36,;22.54,-23.59,;22.55,-22.04,;21.21,-21.27,;23.87,-21.27,;25.21,-22.04,;26.67,-21.55,)| | ||
Structure |