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TargetfMet-Leu-Phe receptor
LigandBDBM50419380
Substrate/Competitorn/a
Meas. Tech.ChEMBL_788190 (CHEMBL1919337)
IC50 501±n/a nM
Citation Morley, ADCook, AKing, SRoberts, BLever, SWeaver, RMacdonald, CUnitt, JFagura, MPhillips, TLewis, RWenlock, M Discovery of pyrazoles as novel FPR1 antagonists. Bioorg Med Chem Lett21:6456-60 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
fMet-Leu-Phe receptor
Name:fMet-Leu-Phe receptor
Synonyms:FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:Enzyme Catalytic Domain
Mol. Mass.:38456.14
Organism:Homo sapiens (Human)
Description:gi_4503779
Residue:350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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  Blast E-value cutoff:
BDBM50419380
n/a
NameBDBM50419380
Synonyms:CHEMBL1916283
TypeSmall organic molecule
Emp. Form.C24H30N4O3S
Mol. Mass.454.585
SMILESC[C@@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1)C(C)(C)C |r|
Structure
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