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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M3 | ||
| Ligand | BDBM50419488 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789189 (CHEMBL1924273) | ||
| IC50 | 0.316±n/a nM | ||
| Citation |  Mete, A; Bowers, K; Chevalier, E; Donald, DK; Edwards, H; Escott, KJ; Ford, R; Grime, K; Millichip, I; Teobald, B; Russell, V The discovery of AZD9164, a novel muscarinic M3 antagonist. Bioorg Med Chem Lett21:7440-6 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M3 | |||
| Name: | Muscarinic acetylcholine receptor M3 | ||
| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 66151.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P20309 | ||
| Residue: | 590 | ||
| Sequence: |
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| BDBM50419488 | |||
| n/a | |||
| Name | BDBM50419488 | ||
| Synonyms: | CHEMBL1921932 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H41N2O3 | ||
| Mol. Mass. | 477.6576 | ||
| SMILES | Cc1ccc(OCC[N+]23CCC(CC2)[C@H](C3)OC(=O)[C@@](C)(N2CCCCC2)c2ccccc2)cc1 |r,wU:19.21,wD:19.20,14.17,(6.31,-15.61,;4.95,-14.89,;3.64,-15.7,;2.29,-14.98,;2.24,-13.45,;.89,-12.73,;-.42,-13.54,;-1.77,-12.81,;-1.82,-11.27,;-.48,-10.51,;-.48,-8.96,;-1.82,-8.18,;-2.6,-9.51,;-1.12,-9.9,;-3.15,-8.96,;-3.15,-10.51,;-4.5,-8.19,;-5.83,-8.97,;-5.83,-10.52,;-7.17,-8.2,;-7.19,-9.74,;-7.18,-6.65,;-5.84,-5.89,;-5.84,-4.35,;-7.18,-3.57,;-8.52,-4.35,;-8.52,-5.9,;-8.51,-8.96,;-9.84,-8.17,;-11.18,-8.93,;-11.2,-10.47,;-9.86,-11.25,;-8.52,-10.49,;3.54,-12.64,;4.89,-13.35,)| | ||
| Structure | 
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