| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50419687 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_800669 (CHEMBL1947791) |
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| IC50 | 0.794328±n/a nM |
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| Citation |  Alcaraz, L; Bailey, A; Cadogan, E; Connolly, S; Jewell, R; Jordan, S; Kindon, N; Lister, A; Lawson, M; Mullen, A; Dainty, I; Nicholls, D; Paine, S; Pairaudeau, G; Stocks, MJ; Thorne, P; Young, A From libraries to candidate: the discovery of new ultra long-acting dibasicß2-adrenoceptor agonists. Bioorg Med Chem Lett22:689-95 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50419687 |
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| n/a |
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| Name | BDBM50419687 |
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| Synonyms: | CHEMBL1947151 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H33N3O2S |
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| Mol. Mass. | 523.688 |
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| SMILES | C[C@@H](NCc1ccccc1-c1ccc(CCNCCc2ccc(O)c3[nH]c(=O)sc23)cc1)c1ccccc1 |r| |
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| Structure | 
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