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TargetAcetylcholine Binding protein
LigandBDBM50419739
Substrate/Competitorn/a
Meas. Tech.ChEMBL_801486
Ki 316.23±n/a nM
Citation Edink EAkdemir AJansen Cvan Elk RZuiderveld Ode Kanter FJvan Muijlwijk-Koezen JESmit ABLeurs Rde Esch IJ Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein. Bioorg Med Chem Lett 22:1448-54 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:ACh-binding protein | Acetylcholine-binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:n/a
Mol. Mass.:26055.52
Organism:Lymnaea stagnalis
Description:Soluble acetylcholine receptor
Residue:229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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  Blast E-value cutoff:
BDBM50419739
n/a
NameBDBM50419739
Synonyms:CHEMBL1946187
TypeSmall organic molecule
Emp. Form.C24H30NO
Mol. Mass.348.5006
SMILESC[N+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC1c2ccccc2CCc2ccccc12 |r|
Structure
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