| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine-binding protein |
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| Ligand | BDBM50419738 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_801486 (CHEMBL1948413) |
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| Ki | 100±n/a nM |
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| Citation |  Edink, E; Akdemir, A; Jansen, C; van Elk, R; Zuiderveld, O; de Kanter, FJ; van Muijlwijk-Koezen, JE; Smit, AB; Leurs, R; de Esch, IJ Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein. Bioorg Med Chem Lett22:1448-54 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine-binding protein |
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| Name: | Acetylcholine-binding protein |
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| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP |
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| Type: | n/a |
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| Mol. Mass.: | 26055.52 |
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| Organism: | Lymnaea stagnalis |
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| Description: | Soluble acetylcholine receptor |
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| Residue: | 229 |
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| Sequence: | MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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| BDBM50419738 |
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| n/a |
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| Name | BDBM50419738 |
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| Synonyms: | CHEMBL1947206 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25NO3 |
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| Mol. Mass. | 351.4388 |
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| SMILES | Oc1cccc(CCN2[C@H]3CC[C@@H]2C[C@@H](C3)OC(=O)c2ccccc2)c1 |r,THB:7:8:15.14.13:11.10| |
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| Structure | 
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