| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 2 |
|---|
| Ligand | BDBM16173 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_838507 (CHEMBL2078135) |
|---|
| Ki | 4700±n/a nM |
|---|
| Citation |  Urakami, Y; Okuda, M; Masuda, S; Akazawa, M; Saito, H; Inui, K Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharm Res18:1528-34 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 2 |
|---|
| Name: | Solute carrier family 22 member 2 |
|---|
| Synonyms: | Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 62348.38 |
|---|
| Organism: | RAT |
|---|
| Description: | Adrenaline alpha2 0 RAT::Q9R0W2 |
|---|
| Residue: | 555 |
|---|
| Sequence: | MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQ
RCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLG
PCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCL
LVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGIC
YQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAM
KIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLA
SVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGII
TPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKE
KRIYLQVKQADRPLS
|
|
|
|---|
| BDBM16173 |
|---|
| n/a |
|---|
| Name | BDBM16173 |
|---|
| Synonyms: | 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride | 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide | Amiloride | Amipramidin | CHEMBL945 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H8ClN7O |
|---|
| Mol. Mass. | 229.627 |
|---|
| SMILES | NC(=N)NC(=O)c1nc(Cl)c(N)nc1N |
|---|
| Structure | 
|
|---|
Search and Browse
