Reaction Details | |||
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Target | Solute carrier family 22 member 6 | ||
Ligand | BDBM50344967 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_836287 (CHEMBL2076300) | ||
Ki | 9200±n/a nM | ||
Citation | Uwai, Y; Saito, H; Hashimoto, Y; Inui, K Inhibitory effect of anti-diabetic agents on rat organic anion transporter rOAT1. Eur J Pharmacol398:193-7 (2000) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Solute carrier family 22 member 6 | |||
Name: | Solute carrier family 22 member 6 | ||
Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 60784.17 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_838479 | ||
Residue: | 551 | ||
Sequence: |
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BDBM50344967 | |||
n/a | |||
Name | BDBM50344967 | ||
Synonyms: | 2-[(4-Isopropyl-cyclohexanecarbonyl)-amino]-3-phenyl-propionic acid | A-4166 | AY-4166 | CHEMBL783 | DJN-608 | NATEGLINIDE | SDZ-DJN-608 | Starlix | ||
Type | Small organic molecule | ||
Emp. Form. | C19H27NO3 | ||
Mol. Mass. | 317.4226 | ||
SMILES | CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](Cc1ccccc1)C(O)=O |r,wU:6.9,wD:12.12,3.2,(9.97,-8.16,;11.31,-7.39,;12.64,-8.16,;11.31,-5.85,;12.64,-5.08,;12.64,-3.53,;11.3,-2.78,;9.97,-3.55,;9.97,-5.08,;11.3,-1.24,;12.63,-.46,;9.96,-.47,;9.96,1.07,;8.62,1.83,;7.29,1.06,;5.95,1.82,;4.63,1.05,;4.62,-.49,;5.96,-1.27,;7.29,-.49,;11.29,1.84,;12.62,1.08,;11.28,3.38,)| | ||
Structure |