| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
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| Ligand | BDBM50022271 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838299 (CHEMBL2076247) |
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| IC50 | 1300±n/a nM |
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| Citation |  Mulato, AS; Ho, ES; Cihlar, T Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. J Pharmacol Exp Ther295:10-5 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 6 |
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| Name: | Solute carrier family 22 member 6 |
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| Synonyms: | OAT1 | Organic anion transporter 1 | PAH transporter | PAHT | Renal organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | hOAT1 | hPAHT | hROAT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61831.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1487359 |
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| Residue: | 563 |
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| Sequence: | MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN
GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI
VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV
AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE
GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS
IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE
LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQT
RQQQEHQKYMVPLQASAQEKNGL
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| BDBM50022271 |
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| n/a |
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| Name | BDBM50022271 |
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| Synonyms: | 2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylphenyl)propanoic acid | 3-Benzoyl-alpha-methylbenzeneacetic acid | 3-Benzoylhydratropic acid | CHEMBL571 | Dexketoprofen trometamol | KETOPROFEN | L'Acide (benzoyl-3-phenyl)-2-propionique | Orudis (TN) | m-Benzoylhydratropic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14O3 |
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| Mol. Mass. | 254.2806 |
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| SMILES | CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1 |
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| Structure | 
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