| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A3 |
|---|
| Ligand | BDBM50391007 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_838743 (CHEMBL2078569) |
|---|
| Ki | 1200±n/a nM |
|---|
| Citation |  Takeuchi, A; Masuda, S; Saito, H; Hashimoto, Y; Inui, K Trans-stimulation effects of folic acid derivatives on methotrexate transport by rat renal organic anion transporter, OAT-K1. J Pharmacol Exp Ther293:1034-9 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier organic anion transporter family member 1A3 |
|---|
| Name: | Solute carrier organic anion transporter family member 1A3 |
|---|
| Synonyms: | OAT-K1 | OAT-K2 | Oatp1a3 | SO1A3_RAT | Slc21a4 | Slco1a3 | Sodium-independent organic anion transporter K1 | Solute carrier family 21 member 4 | rOAT-K |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 73829.31 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_838743 |
|---|
| Residue: | 670 |
|---|
| Sequence: | MGDLEKGAATHGAGCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGF
INGSFEIGNLLLIIFVSYFGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTIL
PTSNLSSNSFLCMENQTQTLNPAQDPAECVKEVKSLMWIYVLVGNIIRGIGETPIMPLGV
SYIENFAKSENSPLYIGILETGKMIGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIR
WVGAWWIGFLVCAGVNILISIPFFFFPKTLPKEGLQENVDGTENAKEESTEKRPRKKNRG
ITKDFFPFLKSPVLQPDLHAVHPYKVLQVNAFNIYFSFLPKYLENQYGKSTAEVIFLMGV
YNLPAICIGYLIAGFMMKKFKITVKTAAFLAFCLSLSEYSFGFCNFLITCDNVPVAGLTN
SYERDQKPLYLENNVLADCNTRCSCLTKTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMV
FHNCSCIQSPGNSSAVLGLCNKGPECTNKLQYLLILSGFLSILYSFAAIPGYMVFLRCIK
SEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLHWGTQKCGAPGACRMYDINSFRRI
YLGMSAALRGSSYLPAFVIVILTRKFSLPGKINSSEMEIAEMKLTEKESQCTDVHRNPKF
KNDGELKTKL
|
|
|
|---|
| BDBM50391007 |
|---|
| n/a |
|---|
| Name | BDBM50391007 |
|---|
| Synonyms: | LEVOMEFOLIC ACID | LMSR |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H25N7O6 |
|---|
| Mol. Mass. | 459.4558 |
|---|
| SMILES | CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
