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TargetSolute carrier family 22 member 2
LigandBDBM50170653
Substrate/Competitorn/a
Meas. Tech.ChEMBL_836776 (CHEMBL2075301)
Ki 460±n/a nM
Citation Gründemann, D; Köster, S; Kiefer, N; Breidert, T; Engelhardt, M; Spitzenberger, F; Obermüller, N; Schömig, E Transport of monoamine transmitters by the organic cation transporter type 2, OCT2. J Biol Chem273:30915-20 (1998) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Solute carrier family 22 member 2
Name:Solute carrier family 22 member 2
Synonyms:Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2
Type:Enzyme Catalytic Domain
Mol. Mass.:62348.38
Organism:RAT
Description:Adrenaline alpha2 0 RAT::Q9R0W2
Residue:555
Sequence:
MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQ
RCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLG
PCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCL
LVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGIC
YQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAM
KIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLA
SVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGII
TPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKE
KRIYLQVKQADRPLS
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  Blast E-value cutoff:
BDBM50170653
n/a
NameBDBM50170653
Synonyms:(11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 11beta,21-dihydroxypregn-4-ene-3,20-dione | 11beta,21-dihydroxyprogesterone | 17-deoxycortisol | CHEMBL110739 | corticosterone
TypeSmall organic molecule
Emp. Form.C21H30O4
Mol. Mass.346.4605
SMILESC[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO |r,t:9|
Structure
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