| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A4 |
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| Ligand | BDBM46355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838969 (CHEMBL2078430) |
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| Ki | 580±n/a nM |
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| Citation |  Sugiyama, D; Kusuhara, H; Shitara, Y; Abe, T; Sugiyama, Y Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates. Drug Metab Dispos30:220-3 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1A4 |
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| Name: | Solute carrier organic anion transporter family member 1A4 |
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| Synonyms: | Brain digoxin carrier protein | Brain-specific organic anion transporter | OATP-B1 | Oatp1a4 | Oatp2 | SO1A4_RAT | Slc21a5 | Slco1a4 | Sodium-independent organic anion-transporting polypeptide 2 | Solute carrier family 21 member 5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73261.82 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_836631 |
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| Residue: | 661 |
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| Sequence: | MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGL
INGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILP
TSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGIS
YIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRW
VGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGI
TKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLY
MLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTS
YEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVF
QNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKS
EEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLY
LGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTE
D
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| BDBM46355 |
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| n/a |
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| Name | BDBM46355 |
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| Synonyms: | DIGOXIN | MLS000069819 | SMR000059217 | US10668094, Compound Digoxin | cid_2724385 |
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| Type | Small organic molecule |
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| Emp. Form. | C41H64O14 |
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| Mol. Mass. | 780.9385 |
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| SMILES | C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C |t:46| |
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| Structure | 
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