| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A4 |
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| Ligand | BDBM50375594 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838984 (CHEMBL2078501) |
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| Ki | 156000±n/a nM |
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| Citation |  Sugiyama, D; Kusuhara, H; Shitara, Y; Abe, T; Sugiyama, Y Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates. Drug Metab Dispos30:220-3 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1A4 |
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| Name: | Solute carrier organic anion transporter family member 1A4 |
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| Synonyms: | Brain digoxin carrier protein | Brain-specific organic anion transporter | OATP-B1 | Oatp1a4 | Oatp2 | SO1A4_RAT | Slc21a5 | Slco1a4 | Sodium-independent organic anion-transporting polypeptide 2 | Solute carrier family 21 member 5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73261.82 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_836631 |
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| Residue: | 661 |
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| Sequence: | MGKSEKRVATHGVRCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGL
INGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYETILP
TSNVSSNSFFCVENRSQTLNPTQDPSECVKEMKSLMWIYVLVGNIIRGIGETPIMPLGIS
YIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRW
VGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVDGTENAKEKKHRKKAKEEKRGI
TKDFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLY
MLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTS
YEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVF
QNCSCIQSSGNSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKS
EEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLY
LGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTE
D
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| BDBM50375594 |
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| n/a |
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| Name | BDBM50375594 |
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| Synonyms: | TAUROCHOLATE |
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| Type | Small organic molecule |
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| Emp. Form. | C26H45NO7S |
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| Mol. Mass. | 515.703 |
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| SMILES | C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |r| |
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| Structure | 
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