| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 3 |
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| Ligand | BDBM50420192 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_836621 (CHEMBL2077362) |
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| IC50 | 1760±n/a nM |
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| Citation |  Martel, F; Gründemann, D; Calhau, C; Schömig, E Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn Schmiedebergs Arch Pharmacol363:40-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 3 |
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| Name: | Solute carrier family 22 member 3 |
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| Synonyms: | EMT | EMTH | Extraneuronal monoamine transporter | OCT3 | Organic cation transporter 3 | S22A3_HUMAN | SLC22A3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61292.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_934315 |
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| Residue: | 556 |
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| Sequence: | MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALA
ERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNR
SAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYG
RIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRR
IVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKK
GDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFT
SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVA
CLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFG
GIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHS
CKCGRNKKTPVSRSHL
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| BDBM50420192 |
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| n/a |
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| Name | BDBM50420192 |
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| Synonyms: | CHEMBL2074851 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N3 |
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| Mol. Mass. | 356.4828 |
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| SMILES | CC[n+]1c(CC2C=C(C)N=C(N2C)c2ccccc2)ccc2ccccc12 |c:9,t:6| |
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| Structure | 
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