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TargetSnake venom metalloproteinase BaP1
LigandBDBM50420344
Substrate/Competitorn/a
Meas. Tech.ChEMBL_840308 (CHEMBL2091265)
IC50 4600±n/a nM
Citation Villalta-Romero, FGortat, AHerrera, AEArguedas, RQuesada, Jde Melo, RLCalvete, JJMontero, MMurillo, RRucavado, AGutiérrez, JMPérez-Payá, E Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design. ACS Med Chem Lett3:540-543 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Snake venom metalloproteinase BaP1
Name:Snake venom metalloproteinase BaP1
Synonyms:Bap-1 | Hemorrhagic metalloproteinase BaP1 | SVMP | VM1B1_BOTAS
Type:PROTEIN
Mol. Mass.:45929.07
Organism:Bothrops asper
Description:ChEMBL_840308
Residue:408
Sequence:
MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTELPKGAVQPKYEDAMQYEFK
VNGEPVVLHLEKNKGLFSEDYSETHYSPDGRKIITYPSFEDHCYYHGRIENDADSTASIS
ACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWESYEPI
KKASQSNLTPEQQRFSPRYIELAVVADHGIFTKYNSNLNTIRTRVHEMLNTVNGFYRSVD
VHAPLANLEVWSKQDLIKVQKDSSKTLKSFGEWRERDLLPRISHDHAQLLTAVVFDGNTI
GRAYTGGMCDPRHSVGVVRDHSKNNLWVAVTMAHELGHNLGIHHDTGSCSCGAKSCIMAS
VLSKVLSYEFSDCSQNQYETYLTNHNPQCILNKPLLTVSGNELLEAGE
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  Blast E-value cutoff:
BDBM50420344
n/a
NameBDBM50420344
Synonyms:CHEMBL2089172
TypeSmall organic molecule
Emp. Form.C21H35N7O4
Mol. Mass.449.5471
SMILES[#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#8] |r|
Structure
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