| Reaction Details |
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 | Report a problem with these data |
| Target | Snake venom metalloproteinase BaP1 |
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| Ligand | BDBM50292332 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_840308 (CHEMBL2091265) |
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| IC50 | 93300±n/a nM |
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| Citation |  Villalta-Romero, F; Gortat, A; Herrera, AE; Arguedas, R; Quesada, J; de Melo, RL; Calvete, JJ; Montero, M; Murillo, R; Rucavado, A; Gutiérrez, JM; Pérez-Payá, E Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design. ACS Med Chem Lett3:540-543 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Snake venom metalloproteinase BaP1 |
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| Name: | Snake venom metalloproteinase BaP1 |
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| Synonyms: | Bap-1 | Hemorrhagic metalloproteinase BaP1 | SVMP | VM1B1_BOTAS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45929.07 |
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| Organism: | Bothrops asper |
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| Description: | ChEMBL_840308 |
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| Residue: | 408 |
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| Sequence: | MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTELPKGAVQPKYEDAMQYEFK
VNGEPVVLHLEKNKGLFSEDYSETHYSPDGRKIITYPSFEDHCYYHGRIENDADSTASIS
ACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWESYEPI
KKASQSNLTPEQQRFSPRYIELAVVADHGIFTKYNSNLNTIRTRVHEMLNTVNGFYRSVD
VHAPLANLEVWSKQDLIKVQKDSSKTLKSFGEWRERDLLPRISHDHAQLLTAVVFDGNTI
GRAYTGGMCDPRHSVGVVRDHSKNNLWVAVTMAHELGHNLGIHHDTGSCSCGAKSCIMAS
VLSKVLSYEFSDCSQNQYETYLTNHNPQCILNKPLLTVSGNELLEAGE
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| BDBM50292332 |
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| n/a |
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| Name | BDBM50292332 |
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| Synonyms: | 2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium; chloride | 2,3,9,10-tetramethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium | CHEMBL1270849 | CHEMBL2163795 | CHEMBL274189 | GNF-Pf-4086 | PALMATINE |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22NO4 |
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| Mol. Mass. | 352.4031 |
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| SMILES | COc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1OC |
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| Structure | 
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