| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50420809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839813 (CHEMBL2089824) |
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| Ki | >400±n/a nM |
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| Citation |  Pedregal, C; Joshi, EM; Toledo, MA; Lafuente, C; Diaz, N; Martinez-Grau, MA; Jiménez, A; Benito, A; Navarro, A; Chen, Z; Mudra, DR; Kahl, SD; Rash, KS; Statnick, MA; Barth, VN Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor. J Med Chem55:4955-67 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50420809 |
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| n/a |
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| Name | BDBM50420809 |
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| Synonyms: | CHEMBL2088038 | CHEMBL2088039 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28N4O2S |
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| Mol. Mass. | 388.527 |
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| SMILES | CN(C)C(=O)C(CN1CCC2(CC1)OCCc1ccsc21)Cn1cccn1 |
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| Structure | 
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