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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50421106
Substrate/Competitorn/a
Meas. Tech.ChEMBL_842489
Ki 0.21±n/a nM
Citation Fukaya TKodo TIshiyama TKakuyama HNishikawa HBaba SMasumoto S Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands. Bioorg Med Chem 20:5568-82 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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BDBM50421106
n/a
NameBDBM50421106
Synonyms:CHEMBL2088364
TypeSmall organic molecule
Emp. Form.C22H17ClN2O3
Mol. Mass.392.835
SMILESCN(C(=O)Cn1c2cc(ccc2oc1=O)-c1ccccc1)c1ccc(Cl)cc1
Structure
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