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TargetPeripheral-Type Benzodiazepine Receptor
LigandBDBM50421116
Substrate/Competitorn/a
Meas. Tech.ChEMBL_842489
Ki 0.29±n/a nM
Citation Fukaya TKodo TIshiyama TKakuyama HNishikawa HBaba SMasumoto S Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands. Bioorg Med Chem 20:5568-82 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peripheral-Type Benzodiazepine Receptor
Name:Benzodiazepine receptors; peripheral & central
Synonyms:Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR)
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50421116
n/a
NameBDBM50421116
Synonyms:CHEMBL2088374
TypeSmall organic molecule
Emp. Form.C23H20N2O4
Mol. Mass.388.4159
SMILESCOc1ccc(cc1)-c1ccc2oc(=O)n(CC(=O)N(C)c3ccccc3)c2c1
Structure
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