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TargetSonic hedgehog protein
LigandBDBM50421191
Substrate/Competitorn/a
Meas. Tech.ChEMBL_839706
IC50>100±n/a nM
Citation Ohashi TOguro YTanaka TShiokawa ZShibata SSato YYamakawa HHattori HYamamoto YKondo SMiyamoto MTojo HBaba ASasaki S Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors. Bioorg Med Chem 20:5496-506 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sonic hedgehog protein
Name:Sonic hedgehog protein
Synonyms:n/a
Type:Protein
Mol. Mass.:47784.50
Organism:Mus musculus (Mouse)
Description:Q62226
Residue:437
Sequence:
MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGAS
GRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPG
VKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKA
HIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFL
TFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQR
VYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAH
RAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTW
LLDSETMHPLGMAVKSS
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  Blast E-value cutoff:
BDBM50421191
n/a
NameBDBM50421191
Synonyms:CHEMBL2086402
TypeSmall organic molecule
Emp. Form.C25H32N4O5
Mol. Mass.468.5454
SMILESCCC(=O)Cn1c2ccccc2c2n(C)c(C(=O)NC3CCN(CCO)CC3)c(OC)c2c1=O
Structure
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