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TargetBeta-2 adrenergic receptor
LigandBDBM50421324
Substrate/Competitorn/a
Meas. Tech.ChEMBL_841415 (CHEMBL2091584)
Ki 382±n/a nM
Citation Beattie, DBeer, DBradley, MEBruce, ICharlton, SJCuenoud, BMFairhurst, RAFarr, DFozard, JRJanus, DRosethorne, EMSandham, DASykes, DATrifilieff, ATurner, KLWissler, E An investigation into the structure-activity relationships associated with the systematic modification of theß(2)-adrenoceptor agonist indacaterol. Bioorg Med Chem Lett22:6280-5 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50421324
n/a
NameBDBM50421324
Synonyms:CHEMBL2088196
TypeSmall organic molecule
Emp. Form.C25H30N2O3
Mol. Mass.406.5173
SMILESCCc1cc2CC(Cc2cc1CC)NCC(O)c1ccc(O)c2[nH]c(=O)c(C)cc12
Structure
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