| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor and beta-3 adrenergic receptor |
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| Ligand | BDBM50421329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_841415 |
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| Ki | 0.600000±n/a nM |
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| Citation |  Beattie D; Beer D; Bradley ME; Bruce I; Charlton SJ; Cuenoud BM; Fairhurst RA; Farr D; Fozard JR; Janus D; Rosethorne EM; Sandham DA; Sykes DA; Trifilieff A; Turner KL; Wissler E An investigation into the structure-activity relationships associated with the systematic modification of theß(2)-adrenoceptor agonist indacaterol. Bioorg Med Chem Lett 22:6280-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor and beta-3 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor and beta-3 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50421329 |
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| n/a |
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| Name | BDBM50421329 |
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| Synonyms: | CHEMBL2088201 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N2O3 |
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| Mol. Mass. | 406.5173 |
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| SMILES | CCc1cc2CC(C)(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12 |r| |
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| Structure | 
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