| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50421326 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_841421 (CHEMBL2091590) |
|---|
| IC50 | 240±n/a nM |
|---|
| Citation |  Beattie, D; Beer, D; Bradley, ME; Bruce, I; Charlton, SJ; Cuenoud, BM; Fairhurst, RA; Farr, D; Fozard, JR; Janus, D; Rosethorne, EM; Sandham, DA; Sykes, DA; Trifilieff, A; Turner, KL; Wissler, E An investigation into the structure-activity relationships associated with the systematic modification of theß(2)-adrenoceptor agonist indacaterol. Bioorg Med Chem Lett22:6280-5 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46993.24 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
|
|
|
|---|
| BDBM50421326 |
|---|
| n/a |
|---|
| Name | BDBM50421326 |
|---|
| Synonyms: | CHEMBL2088198 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H28N2O2 |
|---|
| Mol. Mass. | 376.4913 |
|---|
| SMILES | CCc1cc2CC(Cc2cc1CC)NCCc1ccc(O)c2[nH]c(=O)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
