| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM22883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_85509 |
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| Kd | 26303±n/a nM |
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| Citation |  Eriks, JC; van der Goot, H; Sterk, GJ; Timmerman, H Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles. J Med Chem35:3239-46 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40567.22 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | For the H2 receptor-binding assays, guinea pig striatum was used. |
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| Residue: | 359 |
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| Sequence: | MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSL
AVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYH
QLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
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|
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| BDBM22883 |
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| n/a |
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| Name | BDBM22883 |
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| Synonyms: | CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl)propyl]dimethylamine |
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| Type | Small organic molecule |
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| Emp. Form. | C6H15N3S |
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| Mol. Mass. | 161.268 |
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| SMILES | CN(C)CCCSC(N)=N |
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| Structure | 
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