| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 11 |
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| Ligand | BDBM50422739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321685 (CHEMBL872180) |
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| IC50 | 457±n/a nM |
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| Citation |  Ullmann, H; Meis, S; Hongwiset, D; Marzian, C; Wiese, M; Nickel, P; Communi, D; Boeynaems, JM; Wolf, C; Hausmann, R; Schmalzing, G; Kassack, MU Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. J Med Chem48:7040-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 11 |
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| Name: | P2Y purinoceptor 11 |
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| Synonyms: | P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40366.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1362532 |
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| Residue: | 374 |
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| Sequence: | MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
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| BDBM50422739 |
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| n/a |
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| Name | BDBM50422739 |
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| Synonyms: | CHEMBL413145 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H28F2N6O23S6 |
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| Mol. Mass. | 1299.163 |
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| SMILES | [O-]S(=O)(=O)c1cc(c2c(NC(=O)c3ccc(F)c(NC(=O)c4cccc(NC(=O)Nc5cccc(c5)C(=O)Nc5cc(ccc5F)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c4)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O |
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| Structure | 
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