| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50422862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_362745 (CHEMBL868152) |
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| Kd | 0.063100±n/a nM |
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| Citation |  Rezmann-Vitti, LA; Nero, TL; Jackman, GP; Machida, CA; Duke, BJ; Louis, WJ; Louis, SN Role of Tyr(356(7.43)) and Ser(190(4.57)) in antagonist binding in the rat beta1-adrenergic receptor. J Med Chem49:3467-77 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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| BDBM50422862 |
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| n/a |
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| Name | BDBM50422862 |
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| Synonyms: | 125I-CYP | CHEMBL210309 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20IN3O2 |
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| Mol. Mass. | 413.2534 |
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| SMILES | CC(C)(C)NCC(O)COc1cccc2[nH]c(C#N)c(I)c12 |
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| Structure | 
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