| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM70185 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_453004 (CHEMBL901144) |
|---|
| IC50 | 3162±n/a nM |
|---|
| Citation |  Lambeng, N; Lebon, F; Christophe, B; Burton, M; De Ryck, M; Quéré, L Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: identification of a lead and initial SAR studies. Bioorg Med Chem Lett17:272-7 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM70185 |
|---|
| n/a |
|---|
| Name | BDBM70185 |
|---|
| Synonyms: | 4-methyl-N-(5-methyl-2-pyridinyl)-3-(1-piperidinylsulfonyl)benzamide | 4-methyl-N-(5-methyl-2-pyridyl)-3-piperidinosulfonyl-benzamide | 4-methyl-N-(5-methylpyridin-2-yl)-3-piperidin-1-ylsulfonyl-benzamide | 4-methyl-N-(5-methylpyridin-2-yl)-3-piperidin-1-ylsulfonylbenzamide | MLS001078236 | SMR000713898 | cid_18106804 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H23N3O3S |
|---|
| Mol. Mass. | 373.469 |
|---|
| SMILES | Cc1ccc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N2CCCCC2)nc1 |
|---|
| Structure | 
|
|---|
Search and Browse
