| Reaction Details |
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 | Report a problem with these data |
| Target | 72 kDa type IV collagenase |
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| Ligand | BDBM50423402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458931 (CHEMBL924950) |
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| Ki | 1.4±n/a nM |
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| Citation |  Verma, RP; Hansch, C Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg Med Chem15:2223-68 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 72 kDa type IV collagenase |
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| Name: | 72 kDa type IV collagenase |
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| Synonyms: | 72 kDa gelatinase | 72 kDa type IV collagenase precursor | CLG4A | Gelatinase A | Gelatinase A (MMP-2) | MMP2 | MMP2_HUMAN | Matrix metalloproteinase-2 | Matrix metalloproteinase-2 (MMP 2) | Matrix metalloproteinase-2 (MMP2) | Matrix metalloproteinases 2 (MMP-2) | TBE-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 73870.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08253 |
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| Residue: | 660 |
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| Sequence: | MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
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| BDBM50423402 |
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| n/a |
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| Name | BDBM50423402 |
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| Synonyms: | CHEMBL122711 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10F5N3O6S |
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| Mol. Mass. | 455.313 |
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| SMILES | ONC(=O)CN(Cc1ccccc1[N+]([O-])=O)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F |
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| Structure | 
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