| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine synthase |
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| Ligand | BDBM50423708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_596272 (CHEMBL1050688) |
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| Kd | 25704±n/a nM |
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| Citation |  Salsi, E; Bayden, AS; Spyrakis, F; Amadasi, A; Campanini, B; Bettati, S; Dodatko, T; Cozzini, P; Kellogg, GE; Cook, PF; Roderick, SL; Mozzarelli, A Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature. J Med Chem53:345-56 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteine synthase |
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| Name: | Cysteine synthase |
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| Synonyms: | CSase | CYSK_HAEIN | O-acetylserine (thiol)-lyase | OAS-TL | cysK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33385.00 |
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| Organism: | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
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| Description: | ChEMBL_596272 |
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| Residue: | 316 |
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| Sequence: | MAIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLT
KGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGM
KGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGG
SITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDL
SIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPS
ASERYLSTALFEGIEG
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| BDBM50423708 |
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| n/a |
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| Name | BDBM50423708 |
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| Synonyms: | CHEMBL568828 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H42N6O10S |
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| Mol. Mass. | 654.732 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCSC)C(O)=O |r| |
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| Structure | 
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