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TargetCarbonic anhydrase 2
LigandBDBM50424254
Substrate/Competitorn/a
Meas. Tech.ChEMBL_935016
Ki 12±n/a nM
Citation Balseven HMustafaIsgör MMert SAlim ZBeydemir SOk SKasimogullari R Facile synthesis and characterization of novel pyrazole-sulfonamides and their inhibition effects on human carbonic anhydrase isoenzymes. Bioorg Med Chem 21:21-7 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrases; II & IX
Synonyms:CA-II | CA2 | CAC | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (Human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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BDBM50424254
n/a
NameBDBM50424254
Synonyms:CHEMBL2314162
TypeSmall organic molecule
Emp. Form.C33H24N6O6S
Mol. Mass.632.645
SMILESNS(=O)(=O)c1ccc(NC(=O)c2nn(c(c2C(O)=O)-c2ccccc2)-c2cccc(c2)N=Nc2c(O)ccc3ccccc23)cc1 |w:31.33|
Structure
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