| Reaction Details |
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 | Report a problem with these data |
| Target | Pro-cathepsin H |
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| Ligand | BDBM50425030 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936321 (CHEMBL2321253) |
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| Ki | 129000±n/a nM |
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| Citation |  Sosic, I; Mirkovic, B; Arenz, K; Stefane, B; Kos, J; Gobec, S Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives. J Med Chem56:521-33 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pro-cathepsin H |
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| Name: | Pro-cathepsin H |
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| Synonyms: | CATH_HUMAN | CBSP | CPSB | CTSH | Cathepsin H | Cathepsin H heavy chain | Cathepsin H light chain | Cathepsin H mini chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37402.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459870 |
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| Residue: | 335 |
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| Sequence: | MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
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| BDBM50425030 |
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| n/a |
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| Name | BDBM50425030 |
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| Synonyms: | CHEMBL2312216 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10N4O3 |
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| Mol. Mass. | 258.2328 |
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| SMILES | Oc1c(CNCC#N)cc([N+]([O-])=O)c2cccnc12 |
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| Structure | 
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