| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM50425179 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936874 (CHEMBL2320756) |
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| IC50 | 20330±n/a nM |
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| Citation |  Patil, VS; Nandre, KP; Ghosh, S; Rao, VJ; Chopade, BA; Sridhar, B; Bhosale, SV; Bhosale, SV Synthesis, crystal structure and antidiabetic activity of substituted (E)-3-(Benzo [d]thiazol-2-ylamino) phenylprop-2-en-1-one. Eur J Med Chem59:304-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase |
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| Type: | Protein |
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| Mol. Mass.: | 57088.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00690 |
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| Residue: | 511 |
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| Sequence: | MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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| BDBM50425179 |
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| n/a |
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| Name | BDBM50425179 |
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| Synonyms: | CHEMBL2313587 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13ClN2OS2 |
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| Mol. Mass. | 360.881 |
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| SMILES | CSC(CC(=O)c1ccc(Cl)cc1)=Nc1nc2ccccc2s1 |w:13.14| |
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| Structure | 
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