| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E synthase |
|---|
| Ligand | BDBM50425332 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_933843 (CHEMBL2321397) |
|---|
| IC50 | >30000±n/a nM |
|---|
| Citation |  Kablaoui, N; Patel, S; Shao, J; Demian, D; Hoffmaster, K; Berlioz, F; Vazquez, ML; Moore, WM; Nugent, RA Novel benzoxazole inhibitors of mPGES-1. Bioorg Med Chem Lett23:907-11 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E synthase |
|---|
| Name: | Prostaglandin E synthase |
|---|
| Synonyms: | MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 17112.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 152 |
|---|
| Sequence: | MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
|
|
|
|---|
| BDBM50425332 |
|---|
| n/a |
|---|
| Name | BDBM50425332 |
|---|
| Synonyms: | CHEMBL2315871 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24ClN3O2 |
|---|
| Mol. Mass. | 361.866 |
|---|
| SMILES | CN(C1CCCC1)C(=O)C1CCN(CC1)c1nc2cc(Cl)ccc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
