| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase CDC14A |
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| Ligand | BDBM50425807 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_937592 (CHEMBL2321061) |
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| IC50 | 6000±n/a nM |
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| Citation |  He, Y; Xu, J; Yu, ZH; Gunawan, AM; Wu, L; Wang, L; Zhang, ZY Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold. J Med Chem56:832-42 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase CDC14A |
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| Name: | Dual specificity protein phosphatase CDC14A |
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| Synonyms: | 3.1.3.16 | 3.1.3.48 | CC14A_HUMAN | CDC14 cell division cycle 14 homolog A | CDC14A |
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| Type: | n/a |
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| Mol. Mass.: | 66598.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UNH5 |
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| Residue: | 594 |
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| Sequence: | MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD
TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR
LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS
NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPSLQSEYVHY
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| BDBM50425807 |
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| n/a |
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| Name | BDBM50425807 |
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| Synonyms: | CHEMBL2316902 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H13F3O4 |
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| Mol. Mass. | 422.3528 |
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| SMILES | OC(=O)c1cc2c(C#Cc3cccc(c3)C(F)(F)F)c(oc2cc1O)-c1ccccc1 |
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| Structure | 
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